In Grownups assigned female at beginning, substantial levels of testosterone could be a sign of polycystic ovary syndrome (PCOS). This affliction is very common — up to fifteen% of men and women AFAB of reproductive age have it.

The main period of time happens among four and 6 weeks of your gestation. Illustrations contain genital virilisation for instance midline fusion, phallic urethra, scrotal thinning and rugation, and phallic enlargement; although the role of testosterone is way smaller than that of dihydrotestosterone. There may be also growth in the prostate gland and seminal vesicles.[citation desired]

In human beings, masculinization on the fetal Mind seems, by observation of gender desire in clients with congenital Problems of androgen development or androgen receptor functionality, to generally be connected to practical androgen receptors.[37]

Testosterone is likewise converted to estradiol in adipose tissue (and to a lesser extent in A few other tissues), which happens to be The main supply of estrogen in Gentlemen. Moreover, testosterone is interconvertible with androstenedione, which may be transformed into estrogens. When androstenedione is shaped in adipose tissue, it may be converted to the type of estrogen known as estrone.

It’s not likely — and challenging to convey to — that an Grownup assigned male at birth has greater-than-regular amounts of testosterone.

Androgen receptors arise in numerous vertebrate entire body system tissues, and both males and females respond similarly to similar levels. Significantly differing quantities of testosterone prenatally, at puberty, and through lifetime account for your share of Organic variations in between males and females.

提神及提升体能（对照睾酮缺乏患者体能较佳，但与正常人无异，刻意补充对体能不会有显著的增加）

虽然雄性激素常被认为仅是男性的性激素，但女性亦会产生雄性激素，只是数量较低，负责性欲与性唤起。雄性激素也是男女体内雌性激素的前体。

精囊 · 精腺排泄管 · 攝護腺（尿道嵴／精阜／攝護腺小囊／射精管 · 攝護腺窦／攝護腺小管） · 尿道球腺

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[147] The T-receptor or DHT-receptor advanced undergoes a structural improve that enables it to move in to the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The parts of binding are called hormone response things (HREs), and impact transcriptional activity of certain genes, generating the androgen consequences.

In non-human primates, it might be that testosterone in puberty stimulates sexual arousal, which makes it possible for the primate to ever more search for out sexual ordeals with females and therefore generates a sexual desire for females.

[70] This reaction engages penile reflexes (which include erection and ejaculation) that help in sperm Competitors when more than one male is existing in mating encounters, letting for more manufacture of productive sperm and a higher possibility of reproduction.

Testosterone is provided in the World Overall health Organization's list of critical medicines, which happen to be An important remedies required in the essential well being technique.